Proteins are essential components of cellular life, uniquely translating genetic information into a vast array of molecular ...

Tau behaves abnormally in the brain in people with Alzheimer’s disease. This latest study points to a reason why.

This important study identifies the "H-state" as a potential conformational marker distinguishing amyloidogenic from non-amyloidogenic light chains, addressing a critical problem in protein misfolding ...

Brain volume loss linked to new Alzheimer’s immunotherapies, such as lecanemab, is caused by the removal of amyloid plaques rather than neuronal damage.

A new study indicates that the loss of brain volume associated with the Alzheimer's drug lecanemab shows the drug is working ...

Preclinical studies have shown AT-02 is able to bind to multiple amyloid types and can induce macrophage mediated amyloid phagocytosis and removal. The Food and Drug Administration has granted Orphan ...

Italian researchers have developed a nasal spray showing promise in slowing Alzheimer's progression. Tests on mice with ...

More than 20 unrelated proteins can form amyloid fibrils in ... such as hemorrhage in local respiratory or urogenital tract AL amyloid. Local amyloid deposits are also hallmark pathological ...

Amyloid light-chain (AL) amyloidosis is a bone marrow disorder that, like ATTR-CM, is caused by misfolded proteins. Although ...

the proteins were involved in β2-m amyloid fibril formation. More information: Suguru Yamamoto et al, Mass spectrometry-based ...