The validation of this assessment for low back pain strongly supports the concept of a mechanism-based classification of pain and is a move towards developing better targeted analgesic therapies.

There is a considerable need for novel analgesics that are more effective ... initially focusing on designing and studying the mechanism of GABA aminotransferase (GABA-AT) inactivators that ...

Janjan et al [49] conducted a descriptive study to explore the quality and intensity of pain associated with RT-induced oral mucositis. Daily pain diaries were completed by 14 patients undergoing ...

Researchers tested the effects of the plant’s methanolic extract and an isolated alkaloid substance, palmatine, on mice. The ...

Heterogeneity in the response to analgesics could be explained by the presence of different underlying pain-generating mechanisms in patients with the same disease. Furthermore, the same pain ...