As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

The liver is largely comprised of hepatocytes, but Kupffer cells, endothelial cells and hepatic stellate cells are also present. Long-term machine perfusion holds great promise in the field of ...

The paradigm of stellate ... by stellate cells, antagonists have been tested as both antifibrotic and portal hypotensive agents. Alternatively, delivery of NO to injured liver may have the same ...