Lung, and Blood Institute first demonstrated its suitability for AAV manufacturing. They infected Sf9 cell lines — derived from the fall armyworm — with three different baculoviruses ...

The new partnership will focus on helping patients with chronic lung disease, utilising 4DMT’s novel discovery platform to generate optimised AAV vectors. So far only three commercial gene ...

Adeno-associated viruses (AAV), which consist of a DNA payload enclosed inside a capsid shell, are regularly employed as vectors for this purpose. However, some capsids can be empty following ...

DMT will now look to begin a Phase II dose expansion, with enrolment slated to commence in the second half of this year.