Then, depending on the stimuli that initiated the autophagy process, the cargo is either degraded or recycled. In 2004, fifty years after Novikoff and de Duve observed lysosomes under the electron ...

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have recently developed a ...

SARS-CoV-2 disrupts cholesterol metabolism by using its ORF3a protein to sequester cholesterol in lysosomes, reducing BMP ...

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have recently developed a ...

Scientists have created a novel technology for developing antibody (M6P) conjugates without enzyme modification in vitro, ...

The process of endocytosis is an example of reverse vesicle trafficking, and it plays an important role in nutrition and immunity as well as membrane recycling. Lysosomes break down and thus ...

The biotech is focusing on precision, small-molecule medicines that work via a process known as cellular clearance by activating the lysosome, sometimes referred to as the cell’s recycling and ...

An international research team led by Osaka University has identified a new mechanism crucial for the initiation of autophagy, a self-degradation process cells use to eliminate unneeded or damaged ...

It quelled production of ApoE aggregates within microglia. So far, the findings suggested that subpar lysosomal function, or overactive interferon signaling, could accelerate the process of ApoE/Aβ ...