Princeton University9y
Actor-critic models of the basal ganglia: New anatomical and computational perspectives
A large number of computational models of information processing in the basal ganglia have been developed in recent years. Prominent in these are actor-critic models of basal ganglia functioning which ...
Newly discovered brain cells play a key role in right and left turns
Parkinson's disease is caused by a lack of dopamine in the brain. This affects the basal ganglia, and the researchers ...
New look at dopamine signaling suggests neuroscientists' model of reinforcement learning may need to be revised
Dopamine is a powerful signal in the brain, influencing our moods, motivations, movements, and more. The neurotransmitter is crucial for reward-based learning, a function that may be disrupted in a ...
Nature3y
Molecular mechanisms of L-DOPA-induced dyskinesia
The basal ganglia are structurally and functionally ... (without dyskinesia induction or expression) in response to dopamine-replacement therapy might now be possible. L-DOPA (L-3,4 ...
Medscape7d
Neuropathy in Parkinson’s Disease May Be Related to L-Dopa Exposure
Idiopathic Parkinson’s disease (IPD) is a central nervous system disorder affecting the basal ganglia that is caused by death of dopamine-producing cells in the substantia nigra. Although IPD is ...