However, in neurodegenerative diseases such as Alzheimer's disease (AD), abnormal phosphorylation of Tau leads to its aggregation into neurofibrillary tangles (NFTs), which are one of the hallmark ...

SignalChem Biotech provides diverse recombinant Tau proteins for research, helping advance tau-targeted therapies that may ...

In patients with AD who have seizures, spatial relationships were observed between the epileptogenic focus and tau and amyloid deposition, as well as neurodegeneration.

Researchers have revealed the role of enzyme TYK2 in the aggregation of tau proteins, which contributes to Alzheimer’s ...

Researchers at Baylor College of Medicine, the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas ...

The phase 3 LUCIDITY trial of tau aggregation inhibitor hydromethylthionine ... substances to different parts of the nerve cell. In AD, the protein goes haywire, forming tangles that have been ...

TMEM106b, TDP-43, and p-tau were similarly linked in ALS and AD/LATE brains. “These observations open the door to more in-depth investigations looking into a potential mechanistic link between ...