The authors recount their discovery of how pathogen-induced interleukin 12 production leads to T H 1 T cell polarization. Simultaneously they discovered the suppressive cytokine interleukin 10 ...

A research team from the Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences has revealed that aging specifically impairs the generation of CD8+ tissue resident memory ...

MDNA11 shows significant survival benefits in preclinical glioblastoma models, expanding CD8 + T and NK cells. Bizaxofusp selectively targets human tumor cells and immune-suppress ...

Researchers report results of the first-in-human phase 1 clinical trials of a novel immunotherapy approach for solid tumors ...

Company to share preclinical data across diverse pipeline of iNK, γδ iT, and αβ iT cell therapy programs for oncology and autoimmune disease (AID) – – Preclinical data on development of iPSC-derived ...

In specific experiments, anti-IL-8 or anti-GM-CSF antibodies (10 μg/mL, R&D Systems) were added to Th17 supernatants. Migration of CD8+ T cells, sorted from PBMC of HDs by magnetic microbeads ...

One poster will discuss the successful generation of iPSC-derived CD4+ and CD8+ CAR T cells, showcasing antigen-dependent expansion and IL-2 production. Another will explore universal cloaking of ...

According to the World Health Organization (WHO), cancer remains one of the leading causes of death globally, responsible for ...

This study presents important findings on the role of CXXC-finger protein 1 in regulatory T cell gene regulation and function. The evidence supporting the authors' claims is solid, with mostly ...

2024 — A new study has found a surprising link between high levels of methylmalonic acid and the weakening of CD8+ T cells, shedding light on potential pathways through which aging may promote ...

In this article, we will look at the 10 Most Promising ... an interleukin-15 (IL-15) superagonist designed to activate natural killer (NK) cells and generate CD8+ memory T cells, which are ...