RNA therapeutics promise rapid, personalized and flexible treatments against multiple diseases. In this article, we will ...

Preclinical data shows strong, durable, and precise repression of HBV DNA across in vitro and in vivo models, offering a possible pathway to a functional cure ...

Circular RNA (circRNA) is gaining increasing attention due to its stable structure, its role in gene regulation, and more recently, its involvement in regulatory circuits mediated by other non-coding ...

Rather than training the algorithm on content scraped from the internet, scientists trained the AI on nearly three million ...

Arcturus Therapeutics Holdings Inc. (the “Company”, “Arcturus”, Nasdaq: ARCT), a commercial messenger RNA medicines company focused on the development ...

However, linear RNA has a short half-life, which necessitates frequent administration. By contrast, circular (circ) RNA is more stable than linear RNA, and with an internal ribosome entry site can be ...

In a paper published in Science Bulletin, a Chinese team of scientists made a significant breakthrough in major depressive ...

A new hydrophobic tag enables the high-purity production of a key intermediate in the chemical synthesis of capped mRNA and circular RNA. These RNAs are used in research and therapeutics such as mRNA ...

Conventional targeted RNA-seq methods often require labor-intensive ... non-polyadenylated, and circular RNAs. It also integrates an EM-based model to achieve unbiased transcriptome quantification ...