Nonurinary sodium excretion in afebrile cirrhotic patients without diarrhea is approximately 10 mmol/day. [13] Patients with ascites on no diuretics commonly have renal sodium excretion of < 20 ...

Total paracentesis has also been shown to be as safe as repeated partial paracentesis and to shorten the period of hospitalization -- and may even be performed on an outpatient basis. [34] However ...

There is a growing global burden of liver disease with the current management for complications of liver cirrhosis being reactive as opposed to proactive, affecting outcomes. Management can often be ...

The FDA informed Intercept that it is unable to approve the sNDA in its current form, consistent with the outcome of the Gastrointestinal Drugs Advisory Committee (GIDAC) meeting in September 2024. In ...

The sNDA was submitted to support full approval of OCA for this indication based on data from the COBALT trial, as well as real-world evidence.

Man boobs or gynecomastia can have various causes but our expert highlights that it may sometimes indicate an underlying ...

This scoring system uses five clinical measures of liver disease: albumin and bilirubin levels, prothrombin time, ascites and encephalopathy. 1 Each measure is scored from 1–3, with 3 indicating ...

This further leads to scarring of the liver causing fibrosis/cirrhosis, a condition where the liver becomes ... abdominal distention (ascites), pale-coloured stools, muscle wasting, and swelling in ...

US PMA alfapump approval expected before end of Q1 2025 alfapump was very effective in control of ascites, virtually eliminating the need for large volume paracentesis (LVP) long term Key POSEIDON ...

The damage caused by cirrhosis can’t be undone, however, if the condition is diagnosed early and the underlying cause is ...

Favorable capital market conditions last week enabled the company to raise over $15 million from secondary offerings, and the proceeds allow the Company to fund fully the costs of this upcoming ...