This valuable study presents a thorough analysis of protein abundance changes caused by amino acid substitutions, using structural context to improve predictive accuracy. By deriving substitution ...

When the algorithm converges or attains the maximum iteration count, the adversarial missense mutation sample alongside the objective function value is procured. Although AlphaFold3 has impressive ...

AI models like artificial neural networks and language models help scientists solve a variety of problems, from predicting the 3D structure of proteins to designing novel ... against the true answer ...

To enhance efficiency and decrease the expense of biological experiments, this paper introduces a method to generate mutated proteins through adversarial attacks on the AlphaFold2 (AF2) model. The ...

Finalising the syllabus for the National Eligibility-Entrance Test Undergraduate (NEET-UG) 2025 examination, the ...

A protein has many identities and one of them depends on the arrangement of its amino acids in the three dimensions of space — in other words, its 3D structure ... For example, in 2022, Baker ...

Even our hair, skin, and nails benefit from the added structure ... of protein needed, Sassos recommends multiplying your weight in kilograms by 0.8 to determine your protein intake. (For example ...

Molecular condensates and gene regulation The region of the CPEB4 protein that holds the segment lacks a well-defined three-dimensional structure ... study is a notable example of how ...

A total of nine TNBC spatial archetypes were identified and associated with disease outcomes and actionable features, as well as a tertiary lymphoid structure ... For example, due to its high ...

Tumor-infiltrating lymphocytes, for example ... tertiary lymphoid structures and T-cell tracks. In human NSCLC, CCL19-expressing FRCs were responsible for tertiary lymphoid structure formation ...