eLife4d
Single cell transcriptomics reveals early photoreceptor states, cell-specific transcript isoforms, and cancer-predisposing features
Here, we used deep full-length single-cell RNA-sequencing to distinguish post-mitotic cone and rod developmental states and cone-specific features that contribute to retinoblastomagenesis. The ...
eLife4d
Eed controls craniofacial osteoblast differentiation and mesenchymal proliferation from the neural crest
In this valuable study, the authors used an elegant genetic approach to delete EED at the post-neural crest induction stage. The usage of the single-cell RNA-seq analysis method is extremely suitable ...
gut.bmj2d
Dissecting transcriptional heterogeneity in primary gastric adenocarcinoma by single cell RNA sequencing
Chief cell predominant GA (GA-FG-CCP) is a rare variant of gastric cancer in the fundic gland region predominant of differentiated chief cells. We delineated cellular and differentiation heterogeneity ...