A Golden Gate-based dual-expression vector enables rapid screening, which facilitates efficient isolation of high-affinity cross-reactive antibodies for therapeutic or diagnostic use and provides a ...
The entire development process, from generating a hybridoma cell line to final approval, took seven years, seven months and five days, says Jan van de Winkel, Genmab's chief scientific officer.
Methods: An anti-BDCA2 antibody was generated from mouse hybridoma and humanized by CDR grafting. The afucosylated antibody was then produced using fucosyltransferase inhibitor or a FUT8 knock-out ...
State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China ...
Cell Culture Market. The global cell culture market is poised for significant growth, with projections estimating a rise from ...
The global cell line development market is projected to experience steady growth, with a projected market size of USD 3,124.4 ...
The large-scale production of recombinant proteins in plants is limited by relatively low yields and difficulties in extraction and purification. These problems were addressed by engineering ...
The main idea tested in this work is that host galectin-9 inhibits Mycobacterium tuberculosis (Mtb) growth by recognizing the Mtb cell wall component arabinogalactan (AG) and, as a result, disrupting ...
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