eLife2d
Sphingosine-1-phosphate signaling regulates the ability of Müller glia to become neurogenic, proliferating progenitor-like cells
Campus Chemical Instrument Center, Mass Spectrometry & Proteomics Facility, The Ohio State University, Columbus, USA ...
The Lancet3d
Targeting sphingosine-1-phosphate receptor modulator in SLE: a promising new therapeutic option
The 2021 approval by regulatory agencies of belimumab, a B lymphocyte stimulator (BLyS) inhibitor, and the 2022 approval of anifrolumab, a type I interferon inhibitor, has increased the therapeutic ...
Lequotidiendumedecin.fr16d
Les MICI à l’ère des traitements ciblés
Les modulateurs de la sphingosine 1 phosphate en lice dans le Crohn Autre innovation dans le cadre des MICI, les modulateurs ...
ahajournals.org19d
Abstract 4120623: Sphingosine Kinase 1 Is Integral For Elastin Deficiency-induced Arterial Hypermuscularization
Introduction: Defective elastic lamellae and smooth muscle cell (SMC) accumulation are characteristics of diverse obstructive arterial diseases (e.g., atherosclerosis, pulmonary hypertension, and ...
ahajournals.org1mon
Targeting Sphingosine-1-Phosphate Signaling to Prevent the Progression of Aortic Valve Disease
To date, there is no pharmacological therapy available to prevent AVD progression. Because valve calcification is the hallmark of AVD and S1P (sphingosine-1-phosphate) plays an important role in ...
eLife6y
Mitochondria-specific photoactivation to monitor local sphingosine metabolism and function
Many lipids are found in mitochondria including one called sphingosine, which is a common component of many other cell membranes too. Sphingosine can increase the concentration of calcium ions inside ...