The Dow topped 45,000 for the first time but Wall Street’s main indexes fell on Wednesday, with the Nasdaq leading declines as technology stocks slumped ahead of the Thanksgiving holiday. Meanwhile, investors focused on the Federal Reserve’s next move following an in-line inflation reading.

The Wall Street major averages were mixed on Wednesday, as investors received a slew of economic data. Early on and the S&P 500 (SP500) was -0.1%, the Dow (DJI) was +0.1%, and the Nasdaq Composite (COMP:IND) was -0.