Objective Systemic lupus erythematosus (SLE) is an autoimmune disease characterised by a loss of immune tolerance, affecting ...
Objectives Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of unknown aetiology that can affect almost any ...
Intro/Background A decline of urine protein-to-creatinine ratio (UPCR) to < 0.5 is associated with better long-term preservation of kidney function in lupus nephritis (LN). UPCR < 0.5 defines complete ...
Inclusion of patient-reported outcomes is important in SLE clinical trials as they allow capture of the benefits of a proposed intervention in areas deemed pertinent by patients. We aimed to compare ...
Objective Circadian rhythm disruption (CRD) has been associated with inflammation and immune disorders, but its role in SLE progression is unclear. We aimed to investigate the impact of circadian ...
3 Division of Rheumatology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Great Neck, NY, USA 4 Division of Rheumatology, Allergy and Immunology, University of California San ...
Objective Systemic autoimmune rheumatic diseases (SARDs) encompass a diverse group of complex conditions with overlapping clinical features, making accurate diagnosis challenging. This study aims to ...
Background Some countries face restrictions to prescribe Chloroquine (CQ) and Hydroxychloroquine (HCQ) during pregnancy, due to report of ocular toxicity in rodents and potential genotoxicity. The aim ...
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Describe why combination of anticoagulation and corticosteroids is the cornerstone treatment of CAPS and that life-threatening CAPS episodes should be treated with a triple-therapy including ...
Background The high heterogeneity in systemic lupus erythematosus (SLE) implies that differential treatment may be required for different patient strata, hence there is an increased need of accurate ...
Objective Hydroxychloroquine (HCQ) is an antimalarial drug employed in the treatment of systemic lupus erythematosus (SLE). Prior studies reported inconsistent results regarding the association ...