The ability to characterize the pulmonary circulation more fully paved the way for many advances. In the 1950s, Dr David ...

BACKGROUND: Coagulation factor XI (FXI) inhibitors are a promising and novel class of anticoagulants, but a recent animal study found that FXI inhibition exacerbated diastolic dysfunction and heart ...

BACKGROUND: Cardiomyocytes in the adult human heart show a regenerative capacity, with an annual renewal rate of ≈0.5%. Whether this regenerative capacity of human cardiomyocytes is employed in heart ...

Kawasaki disease (KD), an acute self-limited febrile illness that primarily affects children <5 years old, is the leading cause of acquired heart disease in developed countries, with the potential of ...

Co–first author and co-chair. Circulation is available at www.ahajournals.org/journal/circ The American Heart Association makes every effort to avoid any actual or ...

Many studies have explored whether individual plasma protein biomarkers improve cardiovascular disease risk prediction. We sought to investigate the use of a plasma proteomics-based approach in ...

The ability to predict recovery of left ventricular ejection fraction (LVEF) in response to guideline-directed therapy among patients with nonischemic cardiomyopathy is desired. We sought to determine ...

Cardiac resynchronization therapy (CRT) is considered a beneficial and disease-modifying treatment in appropriately selected heart failure (HF) patients. It reduces morbidity and mortality, reverses ...

ED indicates emergency department; CP, chest pain. Data were not reported for items left blank. Defined using creatine kinase-MB in all sources, except troponin was used in References 6 and 8.