Treatment with XG005 resulted in statistically significant and clinically meaningful reduction in post-surgical pain ...

Medically reviewed by Lindsay Cook, PharmD Vicodin (hydrocodone-acetaminophen) and Percocet (oxycodone-acetaminophen) are ...

One of the most consumed drugs in the US – and the most commonly taken analgesic worldwide – may do a lot more than simply ...

The central analgesic mechanism of acupuncture for migraine remains poorly understood. Acupuncture has been shown to become a recommended treatment for migraine sufferers. However, a single ...

Channel modulators and blockers are effective analgesics but often confer unwanted side effects. Mounting evidence points to a role of spinal neuroimmune dysregulation in the pathogenesis of ...

Researchers tested the effects of the plant’s methanolic extract and an isolated alkaloid substance, palmatine, on mice. The ...

Vertex Pharmaceuticals’ investigational non-opioid analgesic suzetrigine failed to outperform placebo. Investors voiced their ...

squamosa have analgesic and anti-inflammatory potential ... effects of the samples analyzed and to elucidate their mechanisms of action, which are not yet fully understood. However, further ...

Extracts of ivy (Hedera helix) have antispasmodic and analgesic effects in phytomedicine ... contribution to understanding the activation mechanism of NPFFR1 and may facilitate the rational ...

Therefore, elucidating the molecular mechanisms of neuropathic pain is an important prerequisite for the rational development of novel analgesic drugs for the therapy of neuropathic pain.