A multinational collaboration co-led by the Garvan Institute of Medical Research has uncovered a potential explanation for why some cancer patients receiving a type of immunotherapy called checkpoint ...

Lymphocyte activation occurs when lymphocytes (B cells or T cells) are triggered through antigen-specific receptors on their cell surface. This causes the cells to proliferate and differentiate ...

CDC42 drives ciliary actin polymerization and ectocytosis. The hyperactivation of ciliary CDC42, along with excessive ...

New in vitro preclinical data show CLN-978 induced similar T cell activation, target B cell depletion, and cytokine ...