The San Francisco 49ers and Buffalo Bills are set to face-off in the Week 13 edition of Sunday Night Football. Before the season began, this matchup was circled ...

There's no two ways about it: the San Francisco 49ers are having a brutal season. Taking the field in Week 1 with sky-high ...

San Francisco 49ers star quarterback Brock Purdy has been given an injury update in time for their Week 13 match up against ...

Cleveland Browns wide receiver Jerry Jeudy is headed back to Denver soaring, and his former Broncos coach and teammates ...

The San Francisco 49ers are reeling and now head to Buffalo for a prime time game. Will they have their starting QB back in the fold?

The 49ers have revealed their latest injury report from Wednesday’s practice before their Sunday Night Football tilt against ...

San Francisco 49ers quarterback Brock Purdy was limited with the right shoulder injury that sidelined him last week and there ...

San Francisco 49ers head coach Kyle Shanahan provided updates on his roster Wednesday ahead of the team's first full practice ...

Brock Purdy threw one short pass in the open portion of practice for the San Francisco 49ers as he remains slowed by an ...

Brock Purdy threw one short pass in the open portion of practice for the San Francisco 49ers as he remains slowed by an injury to his throwing shoulder ...

The San Francisco 49ers were outclassed and embarrassed by the Green Bay Packers in Week 12, and without quarterback Brock ...

It couldn’t have gone a lot worse for the San Francisco 49ers on Sunday at Lambeau Field. They fell to the Green Bay Packers ...