Certain antibodies will be best tested using CRISPR-Cas9 to knock out the gene that encodes the target protein, and checking that the antibody no longer binds to anything. Other antibodies might ...
The signal was absent in lysates of cells in which OPTN had been knocked out using CRISPR-Cas9, confirming the specificity of this antibody. OPTN was distinctively localized to the retinal ...
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