Preclinical data shows strong, durable, and precise repression of HBV DNA across in vitro and in vivo models, offering a possible pathway to a functional cure ...

Circular RNA (circRNA) is gaining increasing attention due to its stable structure, its role in gene regulation, and more recently, its involvement in regulatory circuits mediated by other non-coding ...

Rather than training the algorithm on content scraped from the internet, scientists trained the AI on nearly three million ...

BioNTech said that it is acquiring the Chinese drugmaker Biotheus for $800 million to bolster its cancer strategy. The two ...

Arcturus Therapeutics Holdings Inc. (the “Company”, “Arcturus”, Nasdaq: ARCT), a commercial messenger RNA medicines company focused on the development ...

Scientists at Flinders University in Australia have made a discovery that could change how we understand cancer’s origins.

This valuable study reveals extensive binding of eukaryotic translation initiation factor 3 (eIF3) to the 3' untranslated regions (UTRs) of efficiently translated mRNAs in human pluripotent stem ...

In a paper published in Science Bulletin, a Chinese team of scientists made a significant breakthrough in major depressive ...

Transcription activation of genes by estrogens is driven by enhancers, which are often located within the same Topologically Associating Domain (TAD) as non-targeted promoters. We investigated how ...

These instructions are transcribed into RNA, which then undergoes a crucial editing process called splicing. During splicing, non-coding segments of RNA are removed, and the remaining coding sequences ...

Conventional targeted RNA-seq methods often require labor-intensive ... non-polyadenylated, and circular RNAs. It also integrates an EM-based model to achieve unbiased transcriptome quantification ...