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RNA therapeutics promise rapid, personalized and flexible treatments against multiple diseases. In this article, we will ...

Circular RNA (circRNA) is gaining increasing attention due to its stable structure, its role in gene regulation, and more recently, its involvement in regulatory circuits mediated by other non-coding ...

Orna, a circular RNA startup, acquired ReNAgade earlier this year in a deal meant to access the Cambridge company’s technology for delivering RNA medicines. Now, Orna says the newly combined ...

Differentially expressed circFKBP8(5S,6) is a circular RNA with coding potential identified in control volunteers and patients with major depressive disorder (MDD). cFKBP8 is the protein encoded ...

WATERTOWN, Mass., Nov. 5, 2024 /PRNewswire/ -- Orna Therapeutics, a biotechnology company dedicated to designing and delivering a new class of circular RNA medicines and unprecedented lipid ...

At the heart of molecular biology is the study of genetic material – DNA and RNA – which serve as the fundamental blueprints for life. These nucleic acids are not only essential for understanding how ...

A new hydrophobic tag enables the high-purity production of a key intermediate in the chemical synthesis of capped mRNA and circular RNA. These RNAs are used in research and therapeutics such as mRNA ...