Immune checkpoint blockade (ICB) therapies can be very effective against some cancers by helping the immune system recognize ...

Specialized cells help to create a nurturing environment in which tumour-fighting immune cells can thrive and work to ...

Our cells need to be able to recognize potential invaders as a threat, the key function of the body's innate immune system.

Regenerative medicine holds the extraordinary promise that future patients in need of new cells, tissues or organs will no ...

High mutational load tumors mitigate effects from protein-damaging mutations by up-regulating complexes that buffer against misfolding stress, revealing therapeutic vulnerabilities and suggesting ...

There are several cancer therapies which are often confused, including chemotherapy, immunotherapy and targeted therapy.

Beata Halassy's aggressive form of breast cancer kept returning, until she chose to conduct a self-experiment. A molecular ...

Tumor cells transform fibroblasts into cancer-associated fibroblasts, which have an important immunosuppressive activity on which growth, invasion, and metastasis depend. These activated fibroblasts ...

Duke Cancer Institute researchers have identified potential biomarkers that predict the likelihood for checkpoint inhibitor ...

Researchers recently collaborated on a novel, highly specific strategy to treat type 1 diabetes (T1D) using a tagged beta cell transplant in tandem with localized immune protection provided by ...

My first meeting with the oncologist was the worst. I remember him saying, “You need to prepare yourself that this may not be ...

University of Iowa researchers have landed a ten-million-dollar federal grant to develop a new treatment for ovarian cancer.