Highlights in chronic myeloid leukemia from ASH 2024 include data on efficacy of asciminib over TKIs, benefit from the third-generation TKI olverembatinib, and importance of molecular monitoring.

The allogeneic bone marrow-derived mesenchymal stromal cell (MSC) therapy Ryoncil (remestemcel-L-rknd) has been approved for ...

It is typically seen with advanced leukemia or a form of the disease called acute myeloid leukemia (AML). Only around 2% or 3% of people with leukemia get leukemia cutis. Leukemia cutis causes ...

Oct. 9, 2024 — Researchers have created a CRISPR-based rapid molecular diagnostic for two forms of leukemia that are driven by mutations ... a mechanism by which acute myeloid leukemia (AML ...

Background: Acute myeloid leukemia (AML) is a hematologic tumor with poor prognosis and significant clinical heterogeneity. By integrating transcriptomic data, single-cell RNA sequencing data and ...

The difference between hereditary (germline) and acquired (somatic) gene mutations in cancer can lead to much confusion. This is especially true if you’re hearing about genetic testing for a genetic ...

The effective targeting of RAS-mutant acute myeloid leukemia (AML) still remains a challenge; RAS mutations are tied to relapse to targeted therapy, such as resistance to FLT3 inhibitors due to the ...

Acute Myeloid Leukemia (AML) at the 66 th ASH annual meeting. The additional data presented include data for 21 patients with a FLT3 mutation (FLT3m) who had received fewer than 3 lines of prior ...

Such a jump could become far easier with just a single mutation, according to new research. The virus has a fatality rate of 50 percent in humans, so animal infections need to be carefully monitored ...

of 56% Achieved to Date in Patient with Acute Myeloid Leukemia with Myelodysplasia Related Changes (AML MRC) Prospectively Enrolled in Two Expansion Cohorts; Exceeding Prespecified Target Response ...

A new study by biologists from the Scripps Research Institute shows that a bird flu virus is just a single mutation away from having human-ready receptors. If the H5N1 virus does make the switch ...