Interleukin 10 - Wikipedia
IL-10 is a cytokine with multiple, pleiotropic, effects in immunoregulation and inflammation. It downregulates the expression of Th1 cytokines, MHC class II antigens, and co-stimulatory …
Targeting IL-10 Family Cytokines for the Treatment of Human ... - PubMed
Feb 1, 2019 · Members of the interleukin (IL)-10 family of cytokines play important roles in regulating immune responses during host defense but also in autoimmune disorders, …
Biology and therapeutic potential of interleukin-10 - PMC
The cytokine IL-10 is a key anti-inflammatory mediator ensuring protection of a host from over-exuberant responses to pathogens and microbiota, while playing important roles in other …
The clinical, molecular, and therapeutic features of patients with IL10 ...
Interleukin10 (IL10) and IL10 receptor (IL10R) deficiencies are monogenic inborn errors of immunity (IEI) causing early-onset inflammatory bowel diseases (IBD). In this report, we …
List of Interleukin inhibitors - Drugs.com
Interleukin inhibitors are immunosuppressive agents which inhibit the action of interleukins. Interleukins are a group of cytokines which are synthesized by lymphocytes, monocytes, …
Biology and therapeutic potential of interleukin-10
Apr 18, 2019 · The cytokine IL-10 is a key anti-inflammatory mediator ensuring protection of a host from over-exuberant responses to pathogens and microbiota, while playing important …
Interleukin 10 - an overview | ScienceDirect Topics
Interleukin 10 (IL-10) is an anti-inflammatory cytokine that is a member of the class-2 cytokines. In humans, interleukin 10 is encoded by the IL10 gene (loc: 1q32.1) and is produced primarily by …
Role of Interleukin 10 Transcriptional Regulation in Inflammation …
Interleukin 10 (IL-10) is a cytokine with potent anti-inflammatory properties that plays a central role in limiting host immune response to pathogens, thereby preventing damage to the host and …
IL-10 Family Cytokines IL-10 and IL-22: from Basic Science ... - Cell …
IL-10 family cytokines are powerful immune mediators with versatile functions. Since their discovery, many attempts have been made to modulate these cytokines as therapeutic …
Interleukin-10 in cancer immunotherapy: from bench to bedside
Jun 13, 2023 · IL-10 suppresses an excessive inflammatory response via activation of Janus kinase 1. (JAK1)/signal transducer and activator of transcription (STAT)-3, and enhances …