Neisseria gonorrhoeae - Wikipedia
Neisseria gonorrhoeae, also known as gonococcus (singular) or gonococci (plural), is a species of Gram-negative diplococci bacteria first isolated by Albert Neisser in 1879. [3] An obligate human pathogen, it primarily colonizes the mucosal lining of the urogenital tract; however, it is also capable of adhering to the mucosa of the nose, [4] pharynx, rectum, and conjunctiva. [5]
Clinical manifestations and diagnosis of Neisseria gonorrhoeae ...
Jul 8, 2024 · The growing threat of antimicrobial resistance in N. gonorrhoeae highlights the importance of ensuring the availability of appropriate diagnostic modalities for surveillance. This topic discusses the clinical manifestations and diagnosis of gonorrhea in adults and adolescents.
Gonococcal Infections Among Adolescents and Adults
Because of its high specificity (>99%) and sensitivity (>95%), a Gram stain of urethral discharge or secretions that demonstrate polymorphonuclear leukocytes with intracellular gram-negative diplococci can be considered diagnostic for infection with …
Neisseria Gonorrhoae and their antimicrobial susceptibility …
N. gonorrhoeae is observed as Gram negative diplococci when Gram stained, positive for oxidase, ferments only glucose, and is resistant to colisin . Antibiotic susceptibility testing
Gonorrhea Workup: Approach Considerations, Smears With Gram Stain ...
A Gram stain of urethral or cervical discharge may show gram-negative intracellular diplococci (diagnostic in the male) and PMNs. This is very useful if the physician has easy access to a...
Clinical manifestations and diagnosis of - UpToDate
May 26, 2022 · Due to its high specificity, a Gram stain of a male urethral specimen that demonstrates polymorphonuclear leukocytes with intracellular gram-negative diplococci can be considered diagnostic for infection with N. gonorrhoeae in males .
Gonorrhoea (Neisseria gonorrhoeae infection)
Jul 4, 2024 · Molecular tests are the gold standard for diagnosing N. gonorrhoeae which can be performed in the laboratory or at the point of care. Rapid diagnostic tests are currently under development. Gram stain microscopy is used in some laboratories.
Gonorrhea - Gonorrhea - MSD Manual Professional Edition
Gram stain is sensitive and specific for gonorrhea in men with urethral discharge; gram-negative intracellular diplococci typically are seen. Gram stain is much less accurate for infections of the cervix, pharynx, and rectum and is not recommended for diagnosis at these sites.
Neisseria gonorrhoeae - an overview | ScienceDirect Topics
Neisseria gonorrhoeae is one of the most important sexually transmitted diseases in developed countries. The clinical features and detailed methods for isolation and identification of N. gonorrhoeae can be found in Chapter 5.
Recommendations for the Laboratory-Based Detection of …
Mar 14, 2014 · N. gonorrhoeae culture is required to evaluate suspected cases of gonorrhea treatment failure and to monitor developing resistance to current treatment regimens.