Acrosome reaction - Wikipedia
Acrosomal Reaction. As the sperm approaches the zona pellucida of the egg, which is necessary for initiating the acrosome reaction, the membrane surrounding the acrosome fuses with the plasma membrane of the sperm's head, exposing the contents of the acrosome.
Acrosome Definition, Function, Reaction and Exocytosis
When the spermatozoa (or primary ligands of the sperm) come into contact with the jerry layer that surrounds the female gamete (the egg) acrosome reaction/exocytosis is initiated. Before the sperm can undergo acrosome exocytosis, it goes through a process known as capacitation.
Acrosome Reaction - an overview | ScienceDirect Topics
The acrosome reaction (AR) is the fusion between the outer acrosomal membrane and the overlying plasma membrane, at multiple points, resulting in vesiculation and loss of the fused outer acrosomal membrane/plasma membrane. From: Mechanisms of Development, 2018. Add to Mendeley. Set alert. Chapters and Articles.
14.2: Fertilization - Biology LibreTexts
Jul 30, 2022 · This initiates a process called the acrosomal reaction in which the enzyme-filled “cap” of the sperm, called the acrosome, releases its stored digestive enzymes. These enzymes clear a path through the zona pellucida that allows sperm to reach the oocyte. Finally, a single sperm makes contact with sperm-binding receptors on the oocyte’s ...
The acrosome reaction | embryology.ch
The acrosome reaction. During the acrosome reaction the contents of the acrosome are released outwardly. The cell membrane of the spermatozoon fuses with the outer membrane of the acrosome. The contents of the acrosome flow out through the resulting pores. Fig. 32 - Acrosomal reacting spermatozoon. 1. Pores. 2. Emerging of the acrosomal contents.
Acrosome Reaction - an overview | ScienceDirect Topics
The acrosome reaction. When a sperm cell makes contact with the zona pellucida it undergoes morphological changes which are termed the acrosome reaction. The acrosome is a large secretory vesicle, located at the anterior part of sperm cells, surrounded by a membrane and containing a number of enzymes which include hyaluronidase and acrosin.
Mechanism of sperm capacitation and the acrosome reaction: …
After binding to the egg ZP, the spermatozoon undergoes an exocytotic process called the acrosome reaction (AR). 5, 6, 7, 8 This event is required for fertilization, because it enables passage of the spermatozoon through the ZP and its subsequent fusion with the egg oolema.
Mechanism of Acrosome Biogenesis in Mammals - PMC
Abstract. During sexual reproduction, two haploid gametes fuse to form the zygote, and the acrosome is essential to this fusion process (fertilization) in animals. The acrosome is a special kind of organelle with a cap-like structure that covers the anterior portion of …
Mechanisms That Protect Mammalian Sperm from the Spontaneous Acrosome …
Prior to penetrating the oocyte, mammalian spermatozoa should undergo a highly regulated process called the acrosome reaction (AR). The physiological AR is a precise regulated Ca 2+ -dependent exocytotic process induced by the sperm–oocyte contact, causing a rapid increase in intracellular Ca 2+ concentrations, thereby initiating the AR [1, 2].
Chapter 10 - Capacitation and Acrosome Reaction: Histochemical ...
Consequently, failure of acrosomal exocytosis represents a common etiology in defective spermatozoa of male infertility patients that have failed in vitro fertilization (IVF) in a clinical setting; accounting for as much as 29 percent of unexplained male infertility cases [5, 6].