Lung cancer cytology: potential pitfalls and mimics - a review
Cytology plays an important role in the initial evaluation and diagnosis of patients with lung cancer. Various sampling techniques are currently available to procure specimens for cytologic evaluation of lung tumors.
Lung cancer cytology: potential pitfalls and mimics - a review
Mar 25, 2010 · This article focuses on the main classification of primary lung carcinoma - small cell carcinoma, adenocarcinoma and squamous cell carcinoma - with potential mimics discussed under each tumor category.
Lung Cytopathology (Bronchial and Aspiration Cytology) - PMC
This chapter is focused on the discussion and review of cytomorphological features of benign and malignant respiratory lesions.
The utility of cytology in the diagnosis of adenocarcinoma lung: A ...
Pulmonary adenocarcinoma harbors various molecular abnormalities that include epidermal growth factor mutation, anaplastic lymphoma kinase gene re-arrangement, K-RAS mutations. The availability of targeted therapy against these molecular markers …
Lung cancer cytology and small biopsy specimens: diagnosis, …
Sep 1, 2020 · Morphologic and molecular subtyping of non-small cell lung carcinoma, which must often be performed on cytologic or small histologic biopsy specimens, is necessary for both standardization of research and for a personalized approach to therapy.
Immunocytochemistry of cytology specimens for predictive …
Dec 31, 2019 · With a growing number of predictive biomarkers that have emerged in non-small cell lung carcinoma (NSCLC), there has been a paradigm shift in the management of these patients. Of the various predictive biomarker testing methods, immunohistochemistry (IHC) is the most widely available, cost-effective, and commonly used methods.
Lung Cancer Cytology: Can Any of the Cytological Methods …
Background: Diagnosis of lung cancer can be made in two ways: histopathological and cytopathological. Cytological methods in the diagnosis of lung lesions are generally thought to be one of the most successful tactics.
The role of cytology in molecular testing and personalized medicine …
Dec 4, 2018 · Cytology is a viable and underused medium for obtaining molecular testing in lung cancer. There are various obstacles to the widespread adoption of molecular diagnostics using cytologic specimens, ...
Immunocytochemistry for Predictive Biomarker Testing in Lung Cancer ...
In a recent article, key questions of diagnostic IHC in lung cancer have been addressed, and practice recommendations have been made both for histological and cytological specimens. 27 In this review, we discuss the role of preanalytical, analytical, and postanalytical factors that influence the success of ICC testing in various cytology ...
Advances in cytology of lung cancer - ScienceDirect
Sep 1, 2021 · Accurate diagnosis and molecular testing of lung cancer is possible on all types and preparations of cytology specimens. Appropriate specimen handling strategy, knowledge about genomic variations and concurrent cytomorphology and proper validation of molecular testing algorithms are crucial elements for successful application of cytopathology ...